The Hypocritic Oath

Lipid Ratios

Posted in Uncategorized by trinkwasser on August 28, 2009

You” be lucky nowadays if you can even get a Full Lipid Panel, let alone an NMR particle count or any of the other more subtle checks on your lipids.

This is a classic old paper

Ratio of triglycerides to HDL cholesterol is an indicator of LDL particle size in patients with type 2 diabetes and normal HDL cholesterol levels

which looks at the lipid ratios as an indicator of LDL particle size and number

(the full paper is only available as a pdf)

Here’s another

Triglyceride–to–HDL Cholesterol Ratio in the Dyslipidemic Classification of Type 2 Diabetes

which isn’t quite so positive.

There’s another paper I want to add but currently can’t find looking at the trigs/HDL ratio as a marker for insulin resistance.

Talk amongst yourselves, I’m currently searching PubMed and have Phoned A Friend, I’ll add it when I refind it

OK, thanks to Alan,

Relationship between Serum Lipoprotein Ratios and Insulin Resistance in Obesity

Attila Brehm, Georg Pfeiler, Giovanni Pacini, Heinrich Vierhapper and Michael Roden

Note here they are looking at severely obese people: what’s interesting is that the IR appears to be worse in “prediabetics” than full diabetics. Look how many previously undiagnosed diabetics and prediabetics they discovered.

Here’s another featuring Gerald Reaven, the inventor of Metabolic Syndrome/Syndrome X

Use of Metabolic Markers To Identify Overweight Individuals Who Are Insulin Resistant

Tracey McLaughlin, MD; Fahim Abbasi, MD; Karen Cheal, MPH; James Chu, MD; Cindy Lamendola, MSN; and Gerald Reaven, MD

Again they are looking at obese people, though insulin resistance also occurs in the non-obese.

Both papers have a bunch of further useful references.

Next time your doctor (or receptionist) refuses you a Full Lipid Panel, print out as many of these as you can and dump them on his/her desk . . .


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